We build the RNA and protein components that turn biological ideas into testable systems.
Many research programs require more than a single molecule. A targeting RNA may need a receptor-binding protein. A nanoparticle may need a therapeutic oligonucleotide, fluorescent label, or chemically attached drug. A structural study may require a purified membrane receptor in a stable lipid environment. Our platform is built to support these connected needs.
From sequence-defined RNA strands to programmable, multifunctional nanoparticles. Modular assembly for targeting, imaging, gene regulation, and drug delivery.
Recombinant production of soluble and membrane proteins in bacterial, insect, and mammalian systems. Specialized purification, detergent screening, and MSP nanodisc stabilization.
Core RNA Concepts
Ribonucleic acid (RNA) is a biological polymer assembled from nucleotide building blocks. In living systems, RNA drives gene expression, protein production, gene regulation, and cellular signaling. Beyond its biological roles, RNA serves as a programmable nanoscale construction material. Because RNA strands naturally fold, bind, and self-assemble through predictable base-pairing rules, they can be engineered into functional molecular nanorobots with specific size, shape, and purpose — including the ability to carry therapeutic cargo to targeted locations.
Ribonucleic acid (RNA) is a biological polymer assembled from nucleotide building blocks. In living systems, RNA drives gene expression, protein production, gene regulation, and cellular signaling. Beyond its biological roles, RNA serves as a programmable nanoscale construction material. Because RNA strands naturally fold, bind, and self-assemble through predictable base-pairing rules, they can be engineered into functional molecular nanorobots with specific size, shape, and purpose — including the ability to carry therapeutic cargo to targeted locations.
RNA Nanotechnology
Our plug-and-play assembly kits enable any lab to construct self-assembling RNA nanorobots from modular strand components. Each kit includes the RNA strands, assembly buffer, a detailed protocol, and full validation documentation — featuring reference gel images and size-distribution data — ensuring reproducible results from the very first reaction.
We engineer custom RNA nanoparticles composed of paired siRNA strands designed to silence specific target genes with precision in diverse cell types. These purpose-built constructs serve as tools for gene-regulation research and therapeutic development programs.
We produce custom RNA tailored to your specific application, incorporating advanced chemistry such as backbone and base modifications for improved stability, along with conjugation of targeting ligands and fluorophores for cell-specific delivery and visualization.
Core Protein Concepts
Proteins are biological molecules made from amino-acid chains that fold into specific three-dimensional structures. They function as enzymes, receptors, transporters, signaling molecules, antibodies, and structural components. Because protein function depends on correct folding, molecular assembly, and stability, recombinant production must preserve more than the amino-acid sequence. The final protein must also retain the structural and functional properties required for its intended experiment.
Proteins are biological molecules made from amino-acid chains that fold into specific three-dimensional structures. They function as enzymes, receptors, transporters, signaling molecules, antibodies, and structural components. Because protein function depends on correct folding, molecular assembly, and stability, recombinant production must preserve more than the amino-acid sequence. The final protein must also retain the structural and functional properties required for its intended experiment.
Protein Technology
We produce recombinant soluble proteins using bacterial, insect-cell, and mammalian expression systems selected according to the target’s folding, solubility, modification requirements, and intended application. Each protein is recovered and purified using an application-specific chromatographic workflow and evaluated for activity.
We develop recombinant membrane proteins using Sf9 insect-cell or Expi293F mammalian expression, followed by membrane enrichment, detergent solubilization, and chromatographic purification. Purified proteins can be maintained in optimized detergent micelles or reconstituted into proteoliposomes or MSP-based nanodiscs.
We evaluate proteins using analytical methods selected around the final experiment rather than relying on a single purity measurement. Testing can confirm molecular identity, purity, aggregation, oligomeric state, stability, ligand binding, and biological activity in its final formulation.
