QC & Validation
Rigorous quality control at every stage — from individual strands to assembled nanostructures.
Quality Commitment
Validation you can trust
Every construct that leaves our facility is backed by comprehensive quality control data. We employ a suite of analytical methods — chosen based on the construct type, modifications, and intended application — to confirm identity, purity, and functional integrity.
Our QC documentation includes reference gel images, chromatograms, mass spectrometry data, and size-distribution profiles, giving you the evidence you need to reproduce results with confidence.
Analytical Methods
How we validate
Gel Electrophoresis
High-resolution denaturing PAGE to confirm RNA length, integrity, and purity of synthesized constructs.
HPLC & LCMS Analysis
Chromatographic and mass spectrometry analysis to verify identity, quantify purity, and detect synthesis byproducts.
Nuclease-Resistance Testing
Assessment of enhanced stability for modified RNA constructs, confirming that chemical modifications confer the intended resistance.
Size-Distribution Analysis
Dynamic light scattering and native gel analysis to evaluate nanoparticle assembly and population homogeneity.